| 30‑Oct‑2017 | Paris Masters | Hard | SF | 14 | 77 | (Q)Filip Krajinovic [SRB] d. (9)Isner | 6-4 6-7(2) 7-6(5) | (ch) | 1.49 | 33.7% | 2.2% | 80.4% | 85.1% | 66.7% | 0/1 | 2:28 |
| 30‑Oct‑2017 | Paris Masters | Hard | QF | 14 | 17 | (9)Isner d. (13)Juan Martin Del Potro [ARG] | 6-4 6-7(5) 6-4 | (ch) | 1.24 | 17.2% | 4.6% | 69.0% | 85.0% | 66.7% | 0/0 | 2:10 |
| 30‑Oct‑2017 | Paris Masters | Hard | R16 | 14 | 8 | (9)Isner d. (6)Grigor Dimitrov [BUL] | 7-6(10) 5-7 7-6(3) | | 0.83 | 19.1% | 3.1% | 78.6% | 74.8% | 53.6% | 10/12 | 2:45 |
| 30‑Oct‑2017 | Paris Masters | Hard | R32 | 14 | 25 | (9)Isner d. Diego Schwartzman [ARG] | 7-6(2) 6-7(11) 6-3 | (ch) | 0.89 | 22.3% | 3.1% | 69.2% | 74.4% | 60.0% | 4/4 | 2:34 |
| 9‑Oct‑2017 | Shanghai Masters | Hard | R16 | 16 | 54 | Viktor Troicki [SRB] d. (12)Isner | 6-4 7-6(4) | | 0.35 | 13.4% | 3.0% | 71.6% | 70.8% | 63.2% | 2/3 | 1:07 |
| 9‑Oct‑2017 | Shanghai Masters | Hard | R32 | 16 | 131 | (12)Isner d. (Q)Stefanos Tsitsipas [GRE] | 7-6(2) 7-6(9) | | 0.82 | 14.0% | 2.0% | 72.0% | 75.0% | 57.1% | 5/5 | 1:44 |
| 9‑Oct‑2017 | Shanghai Masters | Hard | R64 | 16 | 73 | (12)Isner d. (Q)Dusan Lajovic [SRB] | 4-6 7-6(5) 7-6(6) | | 0.90 | 27.9% | 1.9% | 69.2% | 83.3% | 53.1% | 0/1 | 2:25 |
| 14‑Aug‑2017 | Cincinnati Masters | Hard | SF | 19 | 11 | (7)Grigor Dimitrov [BUL] d. (14)Isner | 7-6(4) 7-6(10) | (ch) | 0.93 | 16.7% | 0.0% | 72.6% | 75.4% | 69.6% | 1/1 | 2:03 |
| 14‑Aug‑2017 | Cincinnati Masters | Hard | QF | 19 | 60 | (14)Isner d. (WC)Jared Donaldson [USA] | 7-6(4) 7-5 | (ch) | 1.36 | 35.2% | 7.0% | 71.8% | 90.2% | 45.0% | 0/0 | 1:30 |
| 14‑Aug‑2017 | Cincinnati Masters | Hard | R16 | 19 | 87 | (14)Isner d. (WC)Frances Tiafoe [USA] | 7-6(4) 7-5 | | 1.34 | 38.0% | 1.4% | 71.8% | 80.4% | 65.0% | 2/2 | 1:39 |
| 14‑Aug‑2017 | Cincinnati Masters | Hard | R32 | 19 | 175 | (14)Isner d. (WC)Tommy Paul [USA] | 6-3 6-3 | | 2.36 | 37.2% | 0.0% | 69.8% | 93.3% | 61.5% | 0/0 | 0:56 |
| 14‑Aug‑2017 | Cincinnati Masters | Hard | R64 | 19 | 47 | (14)Isner d. Viktor Troicki [SRB] | 7-6(3) 6-4 | | 1.32 | 28.6% | 7.1% | 65.7% | 91.3% | 45.8% | 2/2 | 1:25 |
| 7‑Aug‑2017 | Canada Masters | Hard | R64 | 19 | 31 | Juan Martin Del Potro [ARG] d. (14)Isner | 7-5 7-5 | | 0.79 | 30.0% | 5.0% | 62.5% | 76.0% | 43.3% | 5/7 | 1:49 |
| 20‑Mar‑2017 | Miami Masters | Hard | R32 | 23 | 20 | (16)Alexander Zverev [GER] d. (18)Isner | 6-7(5) 7-6(7) 7-6(5) | | 0.92 | 24.1% | 0.9% | 69.0% | 83.8% | 58.3% | 1/2 | 2:38 |
| 20‑Mar‑2017 | Miami Masters | Hard | R64 | 23 | 71 | (18)Isner d. (WC)Thomaz Bellucci [BRA] | 7-5 7-6(5) | | 1.16 | 18.8% | 4.3% | 55.1% | 86.8% | 61.3% | 0/1 | 1:42 |
| 6‑Mar‑2017 | Indian Wells Masters | Hard | R32 | 22 | 11 | (10)Gael Monfils [FRA] d. (20)Isner | 6-2 6-4 | | 0.61 | 6.8% | 3.4% | 62.7% | 64.9% | 45.5% | 5/8 | 1:08 |
| 6‑Mar‑2017 | Indian Wells Masters | Hard | R64 | 22 | 90 | (20)Isner d. (LL)Mikhail Kukushkin [KAZ] | 7-6(0) 7-6(6) | | 1.37 | 32.9% | 0.0% | 77.1% | 87.0% | 62.5% | 0/0 | 1:36 |
