| 6‑Dec‑2021 | Maia 1 CH | Clay | R32 | 824 | 763 | (Q)Miguel Damas [ESP] d. (PR)Cagnina | 0-6 7-6(5) 6-4 | | 1.16 | 8.6% | 7.5% | 48.4% | 80.0% | 54.2% | 1/2 | 2:20 |
| 15‑Nov‑2021 | Pau CH | Hard | R32 | 822 | 108 | (2)Holger Rune [DEN] d. (Alt)Cagnina | 6-0 7-5 | | 0.47 | 8.5% | 5.1% | 40.7% | 62.5% | 40.0% | 10/15 | 1:10 |
| 8‑Nov‑2021 | Roanne CH | Hard | R32 | 829 | 300 | (WC)Arthur Cazaux [FRA] d. (PR)Cagnina | 6-2 6-2 | | 0.48 | 1.7% | 6.7% | 56.7% | 64.7% | 26.9% | 4/8 | 1:04 |
| 29‑Aug‑2021 | Como CH | Clay | R32 | 759 | 281 | (WC)Flavio Cobolli [ITA] d. (PR)Cagnina | 6-1 3-3 RET | | 0.74 | 7.1% | 9.5% | 54.8% | 69.6% | 36.8% | 3/6 | |
| 16‑Aug‑2021 | Luedenscheid CH | Clay | R16 | 852 | 122 | (4)Daniel Altmaier [GER] d. (PR)Cagnina | 7-6(1) 6-3 | | 0.76 | 2.1% | 7.3% | 57.3% | 63.6% | 41.5% | 10/13 | 1:50 |
| 16‑Aug‑2021 | Luedenscheid CH | Clay | R32 | 852 | 307 | (PR)Cagnina d. Mischa Zverev [GER] | 6-3 6-1 | | 1.58 | 2.2% | 2.2% | 73.3% | 66.7% | 66.7% | 2/3 | 1:03 |
| 9‑Aug‑2021 | San Marino CH | Clay | R32 | 849 | 191 | Holger Rune [DEN] d. (PR)Cagnina | 6-3 6-4 | | 0.73 | 4.4% | 5.9% | 58.8% | 60.0% | 46.4% | 4/7 | 1:44 |
| 8‑Mar‑2021 | M15 Antalya | Clay | R32 | 823 | 543 | Oleksii Krutykh [UKR] d. (Q)Cagnina | 1-6 6-1 6-3 | | | | | | | | | |
| 14‑Feb‑2021 | Potchefstroom 2 CH | Hard | R32 | 941 | 214 | (7)Cem Ilkel [TUR] d. (PR)Cagnina | 6-1 7-6(1) | | 0.73 | 10.3% | 6.2% | 60.8% | 54.2% | 44.7% | 14/18 | 1:38 |
| 7‑Feb‑2021 | Potchefstroom 1 CH | Hard | R16 | 941 | 214 | (6)Cem Ilkel [TUR] d. (PR)Cagnina | 6-2 6-3 | | 0.60 | 8.3% | 4.2% | 41.7% | 70.0% | 46.4% | 0/3 | 1:08 |
| 7‑Feb‑2021 | Potchefstroom 1 CH | Hard | R32 | 941 | 1732 | (PR)Cagnina d. (WC)Khololwam Montsi [RSA] | 6-3 6-1 | | 1.60 | 5.8% | 9.6% | 51.9% | 70.4% | 56.0% | 3/5 | 1:18 |