| 19‑Mar‑2025 | Miami Masters | Hard | R128 | 421 | 35 | Matteo Arnaldi [ITA] d. (WC)Wu | 7-6(3) 4-6 6-3 | | 0.76 | 4.4% | 0.0% | 73.7% | 66.7% | 50.0% | 10/12 | 2:30 |
| 2‑Oct‑2024 | Shanghai Masters | Hard | R32 | 560 | 2 | (3)Carlos Alcaraz [ESP] d. (WC)Wu | 7-6(5) 6-3 | | 0.86 | 10.1% | 1.4% | 71.0% | 73.5% | 50.0% | 2/3 | 1:40 |
| 2‑Oct‑2024 | Shanghai Masters | Hard | R64 | 560 | 29 | (WC)Wu d. (25)Nicolas Jarry [CHI] | 6-2 6-1 | | 2.02 | 4.1% | 2.0% | 63.3% | 93.5% | 38.9% | 2/2 | 1:01 |
| 1‑Apr‑2024 | Houston | Clay | R32 | 298 | 33 | (6)Jordan Thompson [AUS] d. (Q)Wu | 6-4 6-4 | | 0.92 | 5.1% | 5.1% | 59.3% | 65.7% | 58.3% | 6/8 | 1:49 |
| 28‑Aug‑2023 | US Open | Hard | R64 | 86 | 13 | (13)Alex De Minaur [AUS] d. Wu | 6-1 6-2 6-1 | | 0.46 | 1.3% | 8.9% | 50.6% | 50.0% | 43.6% | 11/18 | 1:27 |
| 24‑Jul‑2023 | Atlanta | Hard | R16 | 89 | 9 | (1)Taylor Fritz [USA] d. Wu | 6-4 7-6(5) | | 0.71 | 7.6% | 6.3% | 60.8% | 70.8% | 45.2% | 5/7 | 1:30 |
| 3‑Jul‑2023 | Wimbledon | Grass | R128 | 62 | 10 | (10)Frances Tiafoe [USA] d. Wu | 7-6(4) 6-3 6-4 | | 0.83 | 8.3% | 0.9% | 63.9% | 65.2% | 33.3% | 5/11 | 2:30 |
| 26‑Jun‑2023 | Eastbourne | Grass | R32 | 59 | 41 | (8)Miomir Kecmanovic [SRB] d. Wu | 7-6(4) 7-6(5) | | 0.99 | 7.4% | 1.2% | 61.7% | 72.0% | 54.8% | 3/5 | 1:56 |
| 19‑Jun‑2023 | Halle | Grass | R32 | 59 | 7 | (3)Andrey Rublev [RUS] d. Wu | 6-4 6-7(5) 6-2 | | 0.83 | 1.0% | 5.2% | 56.3% | 68.5% | 45.2% | 6/11 | 2:13 |
| 12‑Jun‑2023 | Stuttgart | Grass | R32 | 64 | 25 | Wu d. (8)Nick Kyrgios [AUS] | 7-5 6-3 | (ch) | 1.30 | 7.4% | 2.9% | 63.2% | 76.7% | 64.0% | 2/2 | 1:08 |
| 29‑May‑2023 | Roland Garros | Clay | R128 | 54 | 24 | (19)Roberto Bautista Agut [ESP] d. Wu | 7-6(4) 6-1 6-1 | | 0.59 | 7.0% | 2.6% | 60.5% | 58.0% | 33.3% | 13/20 | 2:11 |
| 22‑May‑2023 | Geneva | Clay | QF | 59 | 27 | (3)Alexander Zverev [GER] d. Wu | 4-1 RET | | 0.37 | 0.0% | 9.1% | 72.7% | 43.8% | 50.0% | 3/5 | 0:21 |
| 8‑May‑2023 | Rome Masters | Clay | R64 | 57 | 31 | (24)Francisco Cerundolo [ARG] d. Wu | 4-6 6-2 6-3 | | 0.69 | 4.0% | 0.0% | 59.0% | 52.5% | 39.0% | 9/17 | 1:59 |
| 8‑May‑2023 | Rome Masters | Clay | R128 | 57 | 44 | Wu d. Richard Gasquet [FRA] | 3-6 6-3 6-3 | | 1.30 | 6.7% | 1.3% | 57.3% | 76.7% | 59.4% | 0/2 | 1:55 |
| 17‑Apr‑2023 | Barcelona | Clay | R64 | 56 | 48 | Diego Schwartzman [ARG] d. Wu | 6-2 6-2 | (ch) | 0.57 | 1.5% | 1.5% | 64.6% | 40.5% | 56.5% | 6/11 | 1:19 |
| 20‑Mar‑2023 | Miami Masters | Hard | R64 | 64 | 38 | (31)Diego Schwartzman [ARG] d. Wu | 7-6(1) 6-1 | | 0.85 | 5.2% | 3.4% | 70.7% | 63.4% | 41.2% | 3/6 | 1:54 |
| 6‑Mar‑2023 | Indian Wells Masters | Hard | R64 | 67 | 28 | (23)Alejandro Davidovich Fokina [ESP] d. (WC)Wu | 6-4 6-1 | | 0.49 | 5.8% | 0.0% | 58.0% | 67.5% | 34.5% | 2/5 | 1:43 |
| 6‑Feb‑2023 | Dallas | Hard | F | 97 | 39 | Wu d. (5)John Isner [USA] | 6-7(4) 7-6(3) 7-6(12) | (ch) | 0.87 | 5.5% | 1.6% | 68.0% | 79.3% | 68.3% | 3/3 | 2:58 |
| 6‑Feb‑2023 | Dallas | Hard | SF | 97 | 8 | Wu d. (1)Taylor Fritz [USA] | 6-7(3) 7-5 6-4 | (ch) | 0.78 | 4.9% | 0.0% | 59.0% | 70.8% | 64.0% | 9/9 | 2:32 |
| 6‑Feb‑2023 | Dallas | Hard | R16 | 97 | 27 | Wu d. (3)Denis Shapovalov [CAN] | 7-6(1) 6-4 | | 1.15 | 2.6% | 0.0% | 63.2% | 66.7% | 64.3% | 3/5 | 1:33 |
| 29‑Aug‑2022 | US Open | Hard | R32 | 174 | 1 | (1)Daniil Medvedev [RUS] d. Wu | 6-4 6-2 6-2 | | 0.71 | 1.1% | 0.0% | 63.6% | 51.8% | 50.0% | 6/12 | 1:55 |
| 29‑Aug‑2022 | US Open | Hard | R128 | 174 | 35 | Wu d. (31)Nikoloz Basilashvili [GEO] | 6-3 6-4 6-0 | | 1.76 | 11.0% | 2.4% | 64.6% | 79.2% | 62.1% | 6/6 | 1:33 |
| 8‑Oct‑2018 | Shanghai Masters | Hard | R32 | 415 | 12 | (8)Kei Nishikori [JPN] d. (WC)Wu | 3-6 6-0 6-3 | | 0.71 | 4.0% | 1.3% | 62.7% | 68.1% | 32.1% | 5/10 | |
| 8‑Jan‑2018 | Auckland | Hard | R32 | 313 | 38 | (7)David Ferrer [ESP] d. (WC)Wu | 7-6(7) 6-4 | | 0.83 | 5.2% | 5.2% | 47.9% | 67.4% | 44.0% | 9/12 | 2:00 |
| 9‑Oct‑2017 | Shanghai Masters | Hard | R64 | 324 | 47 | Gilles Simon [FRA] d. (WC)Wu | 6-3 6-4 | | 0.68 | 5.2% | 5.2% | 53.4% | 77.4% | 40.7% | 4/7 | 1:15 |